RUOResearch Use Only · Not FDA-cleared

Skin Genomics
Report

Your skin's genetic blueprint. UV sensitivity, intrinsic aging rate, barrier function, melanin pathways, vitamin D synthesis, and dermatological risk -- all in one comprehensive report.

⚠ Research Use Only. Not FDA-cleared or approved. Not intended to diagnose, treat, cure, or prevent any disease. Always discuss findings with a licensed healthcare provider.

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Key variants

RSIDs analyzed in this panel

Representative variants. Full report includes all associated loci with genotyped values, effect sizes, and clinical interpretation.

rs1805007
MC1R R151C · UV sensitivity & melanoma risk
One of the strongest common variants affecting UV response and melanoma risk (OR up to 4.38 in carriers). Your report shows your genotype and personalized guidance.
rs1126809
TYR R402Q · melanin production
Affects tyrosinase activity and UV sensitivity. Your report shows your genotype and personalized guidance.
rs1800470
MMP3 · collagen degradation rate
Affects collagen turnover and skincare responsiveness. Your report shows your genotype and personalized guidance.
rs10741657
CYP2R1 · 25-OH vitamin D synthesis
Affects vitamin D synthesis efficiency. Your report shows your genotype and personalized guidance.
Evidence base

Supporting literature

Hayward et al. Human Molecular Genetics 2022 (MC1R causal SNPs). Sturm et al. J Investigative Dermatology 2016 (pigmentation haplotypes). CYP2R1 rs10741657 -- multiple GWAS vitamin D associations. HLA-Cw6 psoriasis -- Nair et al. Nature Genetics 2006.

Why skin genomics first?

Skin is the body system most visibly affected by your genes -- and the one where genomic insights translate most directly into daily actionable choices. MC1R variants affect which SPF you need not just cosmetically but as a cancer-prevention measure. MMP1 variants affect whether retinoids will meaningfully slow your aging trajectory. This report makes those connections explicit.

Connected to the Skin + Cancer add-on

Your Skin Genomics report is the biological foundation of the Skin + Cancer Connection add-on ($89). If your MC1R or TYR variants flag elevated UV sensitivity here, the add-on panel extends that finding into full melanoma PRS scoring, CDKN2A pathway analysis, and a personalized dermatology surveillance protocol.

⚠ Research Use Only (RUO)

This report is for Research Use Only and is not FDA-cleared, FDA-approved, or CE-IVD certified. Polygenic risk scores and pharmacogenomic findings reflect statistical associations from published peer-reviewed GWAS studies. Results are not diagnostic and do not constitute medical advice. Always consult a licensed physician, genetic counselor, or pharmacist before acting on any finding. © 2026 AuraGen Wellness · auragenwellness.com

Included Report
Included
With every WES or WGS kit
  • MC1R · TYR · SLC45A2 -- pigmentation and UV response pathway
  • MMP1 · MMP3 · COL1A1 -- collagen structure and intrinsic aging rate
  • FLG (Filaggrin) -- skin barrier integrity and eczema susceptibility
  • HLA-Cw6 -- psoriasis susceptibility (independent pathway)
  • CYP2R1 -- vitamin D synthesis efficiency (linked to bone health)
  • Personalized skincare ingredient guidance based on your genotype
Order a kit →↓ Download sample report

⚠ Research Use Only · Not FDA cleared