RUOResearch Use Only · Not FDA-cleared

Skin Genomics
Report

Your skin's genetic blueprint. UV sensitivity, intrinsic aging rate, barrier function, melanin pathways, vitamin D synthesis, and dermatological risk — all in one comprehensive report.

⚠ Research Use Only. Not FDA-cleared or approved. Not intended to diagnose, treat, cure, or prevent any disease. Always discuss findings with a licensed healthcare provider.

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Key variants

RSIDs analyzed in this panel

Representative variants. Full report includes all associated loci with genotyped values, effect sizes, and clinical interpretation.

rs1805007T/C
MC1R R151C · UV sensitivity & melanoma risk
R allele carrier · OR=4.38 for melanoma
rs1126809G/A
TYR R402Q · melanin production
Reduced tyrosinase activity · UV sensitivity ↑
rs1800470A/G
MMP3 · collagen degradation rate
Moderate expression — retinoid skincare indicated
rs10741657A/G
CYP2R1 · 25-OH vitamin D synthesis
Reduced synthesis — supplementation advised
Evidence base

Supporting literature

Hayward et al. Human Molecular Genetics 2022 (MC1R causal SNPs). Sturm et al. J Investigative Dermatology 2016 (pigmentation haplotypes). CYP2R1 rs10741657 — multiple GWAS vitamin D associations. HLA-Cw6 psoriasis — Nair et al. Nature Genetics 2006.

Why skin genomics first?

Skin is the body system most visibly affected by your genes — and the one where genomic insights translate most directly into daily actionable choices. MC1R variants affect which SPF you need not just cosmetically but as a cancer-prevention measure. MMP1 variants affect whether retinoids will meaningfully slow your aging trajectory. This report makes those connections explicit.

Connected to the Skin + Cancer add-on

Your Skin Genomics report is the biological foundation of the Skin + Cancer Connection add-on ($89). If your MC1R or TYR variants flag elevated UV sensitivity here, the add-on panel extends that finding into full melanoma PRS scoring, CDKN2A pathway analysis, and a personalized dermatology surveillance protocol.

⚠ Research Use Only (RUO)

This report is for Research Use Only and is not FDA-cleared, FDA-approved, or CE-IVD certified. Polygenic risk scores and pharmacogenomic findings reflect statistical associations from published peer-reviewed GWAS studies. Results are not diagnostic and do not constitute medical advice. Always consult a licensed physician, genetic counselor, or pharmacist before acting on any finding. © 2026 AuraGen Wellness · auragenwellness.com

Included Report
Included
With every WES or WGS kit
  • MC1R · TYR · SLC45A2 — pigmentation and UV response pathway
  • MMP1 · MMP3 · COL1A1 — collagen structure and intrinsic aging rate
  • FLG (Filaggrin) — skin barrier integrity and eczema susceptibility
  • HLA-Cw6 — psoriasis susceptibility (independent pathway)
  • CYP2R1 — vitamin D synthesis efficiency (linked to bone health)
  • Personalized skincare ingredient guidance based on your genotype
Order a kit →↓ Download sample report

⚠ Research Use Only · Not FDA cleared