RUOResearch Use Only · Not FDA-cleared

GeneMATCH
Compatibility Panel

The first multi-domain genetic compatibility profile -- spanning HLA immune genetics, neurochemical bonding circuits, olfactory receptor variation, and personality-linked loci. Unlock from your existing WES or WGS data. Powers AuraMatch.

⚠ Research Use Only. Not FDA-cleared or approved. Not intended to diagnose, treat, cure, or prevent any disease. Always discuss findings with a licensed healthcare provider.

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Key variants

RSIDs analyzed in this panel

Representative variants. Full report includes all associated loci with genotyped values, effect sizes, and clinical interpretation.

HLA-DRB1
HLA Class II · Immune-mediated attraction
Contributes to the immune-diversity domain of your compatibility score. Your report shows your typing and personalized match context.
OXTR
Oxytocin receptor · Bonding & empathy
Contributes to the neurochemical bonding domain of your compatibility score. Your report shows your genotype and personalized context.
AVPR1A
Vasopressin V1a · Pair-bonding & fidelity
Contributes to the neurochemical bonding domain of your compatibility score. Your report shows your genotype and personalized context.
OR6A2
Olfactory receptor · Chr9q scent compatibility
Contributes to the olfactory domain of your compatibility score. Your report shows your genotype and personalized context.
COMT
COMT Val158Met · Stress resilience & dopamine
Contributes to the personality-linked domain of your compatibility score. Your report shows your genotype and personalized context.
BDNF
BDNF Val66Met · Memory & emotional regulation
Contributes to the personality-linked domain of your compatibility score. Your report shows your genotype and personalized context.
Evidence base

Supporting literature

Wedekind et al. Proc R Soc B 1995 (HLA/MHC body odour preference). Ober et al. Nature Genetics 1997 (HLA dissimilarity in couples). Morin et al. BMC Genetics 2011 (930-couple genome-wide study · Chr9q OR cluster). Walum et al. PNAS 2008 (AVPR1A RS3 & marital quality). Koyama et al. PLOS ONE 2024 (OXTR x COMT epistasis). Andari et al. Molecular Psychiatry 2025 (neurochemical basis of love -- review).

Why genetic compatibility?

Thirty years of peer-reviewed research shows that variation in HLA immune loci, neurochemical bonding circuits, and olfactory receptors all contribute to mate-choice preference and long-term relationship satisfaction. No single locus predicts compatibility with certainty -- but 22 loci across four biological systems produce meaningful directional signals that go far beyond personality questionnaires.

How GeneMATCH™ connects to AuraMatch

Your GeneMATCH™ profile is the key to AuraMatch -- the world's first blind genetic compatibility dating platform. No photos. No face-based algorithms. Users are matched by genomic compatibility alone, then choose when and how to reveal more about themselves. Visit auramatch-ashen.vercel.app to join the waitlist.

OR gene coverage -- an honest note

The four olfactory receptor loci (OR13A1, OR13C2, OR2M3, OR6A2) are callable from WES but OR genes have higher GC content than average exonic regions. Coverage at standard 80x WES depth is generally adequate. We confirm OR locus coverage with our lab partner on a per-sample basis and flag any below-threshold loci in the report.

⚠ Research Use Only (RUO)

This report is for Research Use Only and is not FDA-cleared, FDA-approved, or CE-IVD certified. Polygenic risk scores and pharmacogenomic findings reflect statistical associations from published peer-reviewed GWAS studies. Results are not diagnostic and do not constitute medical advice. Always consult a licensed physician, genetic counselor, or pharmacist before acting on any finding. © 2026 AuraGen Wellness · auragenwellness.com

✦ AuraGen Exclusive · Add-On
$89
Instant unlock · no new kit required
  • HLA-A · B · C · DRB1 · DQA1 · DQB1 -- immune genetics & scent-based attraction (35%)
  • OXTR · AVPR1A · DRD4 · COMT · SLC6A4 · OPRM1 -- neurochemical bonding (30%)
  • OR13A1 · OR13C2 · OR2M3 · OR6A2 -- olfactory receptor variation (20%)
  • MAOA · BDNF · NR3C1 · DRD1 · GABRA2 -- personality-linked loci (15%)
  • Composite compatibility score 0-100 across all four domains
  • Powers AuraMatch -- the world's first blind genetic compatibility dating platform
Unlock this panel →↓ Download sample report

⚠ Research Use Only · Not FDA cleared